SHISEIDO ULTIMUNE Power Infusing Concentrate - The Science behind It

　　之前出席了资生堂ULTIMUNE Workshop，对这瓶ULTIMUNE Power Infusing Concentrate很是兴趣。上网查了一些讯息，就和大家分享。

　　肌肤的免疫能力会随着年龄增长，环境污染以及情绪压力而下降。当肌肤的免疫功能下降，随之而来的就是各种肌肤问题，老化，粗糙，斑点，暗沉，甚至痘痘，过敏等等等。

　　要有年轻健康的肌肤，当然要有强大的免疫系统。资生堂这瓶ULTIMUNE，针对提高肌肤免疫力，给予肌肤力量，对抗造成肌肤伤害的因素。

郎格罕细胞 Langerhans Cells

　　说到肌肤免疫系统，就得了解Langerhans 细胞。

　　资生堂从1991年起，与哈佛皮肤研究中心（Harvard Cutaneous Biology Research Center，CBRC）合作，对肌肤免疫能力进行研究工作。经过20年针对免疫力的研究，发现Langerhans 细胞在免疫系统扮演重要的角色。Langerhans细胞存在肌肤的表皮层，占表皮层细胞约2-5%，Langerhans 细胞是免疫系统里的总指挥，其两大功能包括：

指挥功能

　　当探测到外来侵害，如细菌或有害物质，Langerhans 细胞会发出警报，启动免疫功能。

自卫功能

　　当肌肤受到外界环境影响，会产生刺激响应因子，导致肌肤问题。覆盖Langerhans 细胞的CD39酵素会自我保护，攻击刺激响应因子。

　　The skin's immune system is complex, involving various cells playing different vital roles. Among them all, the Langerhans cell is particularly indispensable. The Langerhans cells exist in the upper layer of the skin epidermis, accounting for 2 to 5% of the total epidermal cells. Langerhans cells are the commander-in-chief of the skin's immune system. They have two main functions:

Command function

　　When detect foreign objects, such as germs or harmful substances, intruding the skin, the cells order the immune system to attack the foreign objects.

Self-defense function

　　When skin is stimulated by external factors, stimulation response factors appear in the skin to cause skin problems. When stimulation response factors are detected, Langerhans cell acts on them to defend itself, using the calming enzyme (CD39) which coats the Langerhans cell.

免疫能力与老化 Self-defense function and aging 

　　随着年龄增长，肌肤的免疫能力会急剧下降。研究结果显示，覆盖Langerhans 细胞的CD39酵素也随着年龄增长而减少。图表显示，26－30岁与49－58岁肌肤里 CD39 酵素的数量，有明显的下降。

　　Shiseido studied the changes in the self-defense function due to aging. The results obtained show that the amount of the calming enzyme on the surface of Langerhans cells is significantly decreased in aged skin  (49-58 years) compared with young skin (26-30 years).

Source: Skin Immune Functions and Shiseido's Research

ULTIMUNE 复方 ULTIMUNE Complex

　　于2014年，Shiseido经过20年的研究，研制了一瓶针对激活Langerhans 细胞的护肤品－－激活肌肤免疫力精华。当中的ULTIMUNE Complex激活免疫力复合物，能直接激活Langerhans 细胞机能，达到修护功效。

　　In 2014, Shiseido launches a new product, ULTIMUNE Power Infusing Concentrate that contains ULTIMUNE Complex. Their innovative ULTIMUNE Complex boosts the power of Langerhans cells to enhance skin's immunity.

试验结果 Proven Results

　　95％女性表示肌肤即时变得嫩滑细致。
　　1周后，86％女性表示肌肤变得更有光泽。
　　4周后，肌肤变得更细致有弹性，皱纹明显减淡。




多重防御力: 加倍强健肌肤
　　当肌肤免疫力处于理想水平，肌肤便能发挥4种天然防御力︰抵抗、保护、再生、强化。ULTIMUNE 重新启动此多重防御力，抵抗对肌肤未来造成的伤害，令肌肤状态升华。

Multi-Defensive Power: Strong, healthier-looking skin.

　　When your skin immunity is in its optimal condition, the skin demonstrates the four natural defensive powers at best—to resist, protect, regenerate and strengthen. ULTIMUNE reignites this multi-defensive power to resist future damage and bring out your skin’s ultimate beauty.

肌肤从此持续健康美丽

　　临床测试证实ULTIMUNE 具有超卓护肤功效，使用ULTIMUNE后，多重防御力上升，测试者年纪逾大，提升效果逾见显著。

Skin that remains strong and beautiful over time.

　　ULTIMUNE’s remarkable effects have been proven by clinical tests. Compared against skin without ULTIMUNE, skin with ULTIMUNE shows an increase in Multi-Defensive Power — the older the user, the higher skin’s multi-defensive power becomes with the use of ULTIMUNE. 

*Tested on 22 participants.
*22人接受测试